We each have unique genetic makeup that influences our risk of disease and is influenced by our diet, supplements, and lifestyle.
Genetics and Personalized Healthcare
- Home
- Genetics and Personalized Healthcare
Dr. Maria Zangara is an expert in the cutting-edge field of individualizing treatment plans based on your unique genetic make-up using a database that can show how your genes are up-regulated or down-regulated by various natural substances and can use this personalized information to help you optimize health throughout your lifetime.
Nutrigenetics
Nutrigenetics is the scientific study of the interaction of nutrition and genes, especially with regard to the prevention or treatment of disease.
Nutrigenomics
Nutrigenomics is a branch of nutritional genomics and is the study of the effects of foods and food constituents on gene expression. This means that nutrigenomics is research focusing on identifying and understanding molecular-level interaction between nutrients and other dietary bioactives with the genome.
Genetics and Personalized Healthcare
Dr. Maria Zangara uses Opus23 Pro, a software program that interprets raw genomic data from 23andMe, a company that performs genomic analysis. It takes your genomic information and brings it to life. Once Dr. Zangara receives your 23 and me genomic report, she will take your raw data from 23andMe and run it through Opus23.
She will then translate it into clinically applicable information that she can use to find relevant treatment for problems you are experiencing and administer therapeutic action or as preventative action, which is what we call precision personalized healthcare.
How Does it Work?
The picture below shows that there are a few problems with a gene called Clock and a gene called PER1. The orange color means there are more SNPs. This gene is a member of the Period family of genes and is expressed in the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This is an example of information that is assessed to determine how to best optimise its function, using supplements, specific foods, mind-body therapies, exercise, and proper sleep habits
What is Opus23?
Opus23 is a software program that allows Dr. Maria Zangara perform a number of sophisticated analytics for discovering the hidden secrets of your DNA. Next, Dr Zangara uses this information to help you make targeted specific changes to enable you to have a healthier lifestyle.
What to Expect during an Opus23 Consult
The Opus visit comes with a complete medical examination, which includes a medical intake, physical examination with urine analysis, and treatment protocol.
Patients receive a personalized printout of their genetic analysis that will consist of:
- General blood type information (ABO, Secretor, A1/A2, Kell and Duffy).
- Genetic exploration of your DNA to analyze mutations.
- Susceptibility analysis of diseases.
- Prevention analysis of diseases.
- Analysis of side effects or benefits to drugs.
- Basic food analysis (beneficial and problematic foods list).
- Environmental analysis which could be causative factors of diseases
- Basic genetics overview
- List of your high yield genetic mutations
- Supplement protocol based on your genetic information
How to Prepare for your Opus23 Consult
- Book an appointment for an Opus23 consult with Dr. Zangara 12 weeks in advance.
- Purchase both the following test kits: www.23andMe.com – Ancestry kit [$99.00] and www.ancestry.com/dna – AncestryDNA [$79.00]
- Carefully follow all the instructions when the kits arrives. Collect a saliva sample, fill out all forms, and mail it back to 23andMe in the pre-paid package immediately.
- Be sure to register your saliva sample tube using the barcode, which identifies it belongs to you, before mailing it back. 23andMe will throw out your sample if it is not registered.
- Provide raw data to Dr Maria Zangara once you’ve received email notification that your test results are ready. You can either supply us with your login information and we will download it for you, or download the raw data file and email it to maria@regenerativehealth.doctor.